With the industry's top trophy in hand, both performers capped remarkable years, Mo'Nique startling fans with dramatic depths previously unsuspected in the actress known for lowbrow comedy and Austrian-born veteran Waltz leaping to fame with his first big Hollywood role.
The blockbuster "Up" won the animated feature Oscar, and the Iraq War drama "The Hurt Locker" took the prize for original screenplay.
"The Hurt Locker" and "Avatar" are tied for the Oscar lead with nine nominations each.
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